博彩-玩博彩策略论坛

陳林，博士，副教授，化學(xué)系，畢業(yè)于吉林大學(xué)。

工作內(nèi)容：教學(xué)科研

通訊地址：齊齊哈爾市文化大街42號化學(xué)與化學(xué)工程學(xué)院化工樓304室

電子郵件：[email protected]

研究領(lǐng)域：計(jì)算生物學(xué)；計(jì)算機(jī)輔助藥物設(shè)計(jì)；環(huán)境計(jì)算毒理學(xué)

招生學(xué)科：無機(jī)化學(xué)，學(xué)科教學(xué)（化學(xué)）

教育及科研經(jīng)歷：

2004-2008年 周口師范學(xué)院化學(xué)化工學(xué)院 本科

2008-2010年 吉林大學(xué)化學(xué)學(xué)院 碩士

2010-2013年 吉林大學(xué)化學(xué)學(xué)院 博士

2016年至今 齊齊哈爾大學(xué)化工學(xué)院 副教授 碩士生導(dǎo)師

榮譽(yù)和獎(jiǎng)勵(lì)

黑龍江省科學(xué)技術(shù)獎(jiǎng)(自然科學(xué)類)三等獎(jiǎng)一項(xiàng)（排名5），齊齊哈爾大學(xué)畢業(yè)設(shè)計(jì)（論文）優(yōu)秀指導(dǎo)教師（2次）.

科研論文

1. S. Wang, R.G. Wang, J.W. Yang, L. Xu, B. Zhao, L. Chen, Molecular mechanism of interactions of SPIN1 with novel inhibitors through molecular docking and molecular dynamics simulations. SAR QSAR Environ. Res. 2025, 36(1), 57-77.

2. Q.X. Bai, R.G. Wang, S.L. Qin, B. Zhao, L. Chen, Binding Selectivity of Inhibitors to BRD2 Uncovered by Molecular Docking and Molecular Dynamics Simulations. Adv. Theor. Simul. 2025, 2401262.

3. W. Chen, L Sang, R.G. Wang, D.H. Zou, L. Chen, Selective inhibition mechanism of three inhibitors to BRD4 uncovered by molecular docking and molecular dynamics simulations. SAR QSAR Environ. 2024, 35(12), 1199-1219.

4. X.N. Yao, L. Chen, B. Zhao, R.G. Wang, Theoretical study on the influence of three different surfactants on the binding of laccase with bisphenol A, J. Mol. Liq. 2024, 403, 124848.

5. R.G. Wang, Y.Q. Lin, B. Zhao, L. Chen, Insight into the molecular recognition of human and polar bear pregnane X receptor by three organic pollutants using molecular docking and molecular dynamics simulations, Environ. Int. 2024, 190, 108926.

6. R.G. Wang, L.X. Duan, B. Zhao, L. Chen, Molecular recognition between volatile molecules and odorant binding proteins 7 by homology modeling, molecular docking and molecular dynamics simulation, J. Sci. Food Agr. 2024, 104(12), 7592-7602.

7. F. Bu, L. Chen, Y. Sun, B. Zhao, R.G. Wang, Insight into the Binding Interaction between PEDCs and hERRγ Utilizing Molecular Docking and Molecular Dynamics Simulations, Molecules, 2024, 29(14), 3256.

8. J.W. Yang, L. Chen, X. Huang, B. Zhao, R.G, Wang. Binding interactions of EDCs to human estrogen‐related receptor gamma deciphered by multiple molecular dynamics and energy calculations, Int. J. Quantum Chem. 2024, 124(1), e27333.

9. L. Chen, X. Huang, Y. Li, B. Zhao, M. Liang, R. Wang, Structural and energetic basis of interaction between human estrogen-related receptor γ and environmental endocrine disruptors from multiple molecular dynamics simulations and free energy predictions, J. Hazard. Mater. 2023,443, 130174.

10. Y.F. Li, L. Chen, Y. Sun, R.G. Wang, B. Zhao, T. Jing, Exploring the effect of surfactants on the interaction between laccase and bisphenol A by molecular docking, molecular dynamics, and energy calculations, J. Mol. Liq. 2023, 382, 121928.

11. Y.F. Li, L. Chen, J. Li, B. Zhao, T. Jing, R.G. Wang, Computational explorations of the interaction between laccase and bisphenol A: influence of surfactant and different organic solvents, SAR QSAR Environ. Res. 2023, 34(12), 963-981.

12. C. Wang, L. Chen, W.X. Tang, B. Zhao, R.G. Wang, Molecular basis of RNA recognition by TBP of HIV‐1 from multiple molecular dynamics simulations and energy predictions, J. Comput. Chem. 2023, 44(13), 1291-1299.

13. R.G. Wang, H. Sun, W. Chen, B. Zhao, L. Chen, Molecular basis of ssDNA recognition by RBM45 protein of neurodegenerative disease from multiple molecular dynamics simulations and energy predictions, J. Mol. Graph. Model. 2023, 118, 108377.

14. Y.F. Li, L. Chen, Z.S. Han, R.G. Wang, T. Jing, B. Zhao, Exploring the effects of mutations on NFAT5‐DNA binding using molecular dynamics simulations and energy calculations, Int. J. Quantum Chem. 2022, 122(21), e26980.

15. C. Wang, L. Chen, R.G. Wang, W.X. Tang, B. Zhao, Effects of the G48M mutant on the dynamics properties and binding mechanism of PR with SQV and ATV, Mol. Simulat. 2022, 48(9), 812-824.

16. H. Sun, W. Chen, L. Chen, W.Q. Zheng, Exploring the molecular basis of UG-rich RNA recognition by the human splicing factor TDP-43 using molecular dynamics simulation and free energy calculation, J. Comput. Chem. 2022, 42(23), 1670-1680.

科研項(xiàng)目

1. 大麻二酚與抗炎鎮(zhèn)痛靶點(diǎn)的識別機(jī)制及藥效團(tuán)模型研究，項(xiàng)目負(fù)責(zé)人，黑龍江省教育廳基本科研業(yè)務(wù)費(fèi)，2024.10—2026.10.

2.不同抗衡離子對陰離子表面活性劑界面性質(zhì)影響的分子模擬研究，項(xiàng)目負(fù)責(zé)人，黑龍江省教育廳基本科研業(yè)務(wù)費(fèi)，2021.01—2023.12.

3. BTB/POZ鋅指蛋白Kaiso對甲基化和非甲基化DNA序列識別機(jī)制的理論研究，項(xiàng)目負(fù)責(zé)人，黑龍江省教育廳基本科研業(yè)務(wù)費(fèi)，2018.01—2020.12.

4. 甲型流感病毒M2蛋白的質(zhì)子傳導(dǎo)機(jī)理及其與藥物結(jié)合的理論研究，項(xiàng)目負(fù)責(zé)人，黑龍江省自然科學(xué)基金，2014.07—2017.07.

專利

1.陳林, 趙冰, 王瑞歌. 一種有機(jī)化合物的制備方法及應(yīng)用, 發(fā)明專利, ZL.202010359623.3, 授權(quán)日期: 2022.06.

專著或教材

1. 陳林, 高爽. 物理化學(xué)經(jīng)典理論體系及應(yīng)用研究, 北京工業(yè)大學(xué)出版社, 2017.10.